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A condition in which a single mutant gene affects more than one distinct characteristic of an individual is referred to as Pleiotropy.

What is Pleiotropy?

  • Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits.
  • Such a gene that exhibits multiple phenotypic expressions is called a Pleiotropic gene.
  • Pleiotropy can arise from several distinct but potentially overlapping mechanisms, such as gene pleiotropy, developmental pleiotropy, and selectional pleiotropy.
  • An example of pleiotropy is phenylketonuria.
  • So, when a single trait mutant gene controls more than one trait it is called Pleiotropy and it can cause the various syndrome.

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