Which event contributed to the end of the peaceful relationship between the Jamestown colonists and the Powhatans?
A) the defeat of the Spanish Armada
B) the marriage of Pocahontas
C) the death of Pocahontas
D) the leadership of John Smith
One of the things that contributed to the end of the peaceful relationship between the Jamestown colonists and the Powhatans was "D) the leadership of John Smith," since Smith was a controversial figure whom the Natives did not trust.